基本情况
Yuwei HU (胡玉伟)，预聘副教授，博士生导师。主要从事刺激响应型DNA功能结构、先进可持续材料、智能生物分析传感及药物递送等方面的研究工作。作为PI主持Career Development Fund(CDF)及Central Research Fund(CRF UIBR)等基金项目(新加坡)，以通讯/第一作者在Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Acc. Chem. Res., Mater. Today, Nano Lett., Adv. Funct. Mater., Small, Chem. Eng. J., Biomaterials, Chem. Sci.,等知名期刊发表论文，出版英文专著一部(Springer Nature)。
联系方式
电子邮箱：huyw53@mail.sysu.edu.cn
通讯地址：广东省珠海市唐家湾中山大学珠海校区太阳网集团tcy8722
教育经历
2010-2013 吉林大学&中科院长春应化所，博士
工作经历
2026-至今 中国·太阳集团(tcy8722·官方网站)SunCityGroup|欢迎莅临，副教授
2018-2025 新加坡科技研究局，Senior Scientist, PI
2016-2017 新加坡国立大学，Research Fellow
2013-2016 以色列耶路撒冷希伯来大学，博士后
科研方向
刺激响应型DNA功能材料、先进可持续生物质新材料、智能生物分析传感及药物递送体系
科研项目
Career Development Fund (CDF), SGD 229,000, PI, 主持
Central Research Fund (CRF UIBR), SGD 600,000, PI, 主持
Industry Alignment Fund Pre-Positioning (IAF-PP), 参与
Manufacturing, Trade, and Connectivity (MTC) Programmatic Fund, 参与
Quantum Engineering Programme (QEP2.0), 参与
论著一览
1. Y. Ke, K. Lan, J.Y. Wong, H. Lu, S. Gao, K. Ryu, F. Chen, W.W. Loh, Z. Dong, J.Y.C. Lim, Z. Dong, X. Chen*, I. Willner*, Y. Hu*, Sustainable DNA-Polysaccharide Hydrogels as Reprocessable Bioplastics, Nat. Commun. 2025, 16, 7467.
2. M.S.M. Ho, A.Z.T. Lim, Y. Ke, W.W. Loh, X.T. Zheng, L. Yang, Z. Dong, F. Wang, J.Y.C. Lim, Y. Hu*, Cascade DNA Structural Transitions Enable Stimuli-Responsive Hydrogels, ACS Appl. Mater. Interfaces, 2025, 17, 27116-27125.
3. Y. Hu*, I. Willner*, Oligo‐Adenine Derived Secondary Nucleic Acid Frameworks: From Structural Characteristics to Applications, Angew. Chem. Int. Ed., 2024, 63, e202412106.
4. S.R. Lee, C.Y.J. Ong, J.Y. Wong, Y. Ke, Z. Dong, J.Y.C. Lim, Y. Hu*, Supramolecular oligo-thymine/melamine nanobridge-driven macroscopic engineering: reprogrammable hydrogels for multi-stimuli responsive architectures, Chem. Eng. J., 2024, 497, 154698.
5. S.R. Lee, C.Y.J. Ong, J.Y. Wong, Y. Ke, J.Y.C. Lim, Z. Dong, Y. Long, Y. Hu*, Programming the Assembly of Oligo-Adenine with Coralyne into a pH-Responsive DNA Hydrogel, ACS Appl. Mater. Interfaces, 2024, 16, 15394–15404.
6. Y. Hu*, S. Gao, H. Lu, S. Tan, F. Chen, Y. Ke, J.Y. Ying*, A self-immolative DNA nanogel vaccine toward cancer immunotherapy, Nano Lett., 2023, 23, 9778–9787.
7. Y. Ke, N. Li, Y. Liu, T. Zhu, S. Wang, Y. Li, G. Lin, Q. Zhang, Y. Hu*, Z. Dong, J. Yin, Z. Liu, Y. Long*, Bio‐Inspired, scalable, and Tri‐Mode Stimuli‐Chromic composite for smart window multifunctionality, Adv. Funct. Mater., 2023, 2305998. (Highlighted by A*STAR Research)
8. Y. Hu*, Y. Ke, I. Willner*, A pH‐Cascaded DNA Hydrogel Mediated by Reconfigurable A‐motif Duplex, i‐Motif Quadruplex, and T·A‐T Triplex Structures, Adv. Funct. Mater., 2023, 2304966.
9. Y. Hu, J.Y. Ying*, A Strong Acid‐Induced DNA Hydrogel Based on pH‐Reconfigurable A‐Motif Duplex, Small, 2023, 2205909.
10. Y. Hu, J.Y. Ying*, Reconfigurable A-motif, i-motif and triplex nucleic acids for smart pH-responsive DNA hydrogels, Mater. Today, 2023, 63, 188−209.
11. Y. Hu, S. Gao, H. Lu, J.Y. Ying*, Acid-resistant and physiological pH-responsive DNA hydrogel composed of A-motif and i-motif toward oral insulin delivery, J. Am. Chem. Soc.,2022, 144, 5461−5470. (Highly Cited Paper)
12. Y. Hu‡, A. Cecconello‡, A. Idili‡, F. Ricci*, I. Willner*, Triplex DNA nanostructures: from basic properties to applications, Angew. Chem. Int. Ed., 2017, 56, 15210– 15233. (‡ equal contribution) (Highly Cited Paper)
13. J. S. Kahn‡, Y. Hu‡, I. Willner*, Stimuli-responsive DNA-based hydrogels: from basic principles to applications, Acc. Chem. Res., 2017, 50, 680−690. (‡ equal contribution) (Highly Cited Paper)
14. Y. Hu, J. S. Kahn, W. Guo, F. Huang, M. Fadeev, D. Harries, I. Willner*, Reversible modulation of DNA-based hydrogel shapes by internal stress interactions, J. Am. Chem. Soc., 2016, 138, 16112−16119.
15. Y. Hu, J. Ren, C.-H. Lu, I. Willner*, Programmed pH-driven reversible association and dissociation of interconnected circular DNA dimer nanostructures, Nano Lett., 2016, 16, 4590−4594.
16. Y. Hu, W. Guo, J. S. Kahn, M. A. Aleman-Garcia, I. Willner*, A Shape‐Memory DNA‐Based Hydrogel Exhibiting Two Internal Memories, Angew. Chem. Int. Ed., 2016, 55, 4210–4214. (Hot Paper)
17. Y. Hu‡, C.-H. Lu‡, W. Guo, M. A. Aleman-Garcia, J. Ren, I. Willner*, A shape memory acrylamide/DNA hydrogel exhibiting switchable dual pH‐responsiveness, Adv. Funct. Mater., 2015, 25, 6867–6874. (‡ equal contribution)
18. J. Ren‡, Y. Hu‡, C.-H. Lu, W. Guo, F. Ricci, I. Willner*, pH-responsive and switchable triplex-based DNA hydrogels, Chem. Sci., 2015, 6, 4190–4195. (‡ equal contribution)
专著：
Y. Hu, F. Li, D. Han, L. Niu, Biocompatible Graphene for Bioanalytical Applications, ISBN 978-3-662- 45694-1, Springer Briefs in Molecular Science, 2015 Springer Nature.